Posted on 2025/12/02
Senior AI Applications Engineer
GeneDx
San Antonio, TX, United States
Qualifications
- You will need a strong foundation in understanding business objectives and communicating effectively, along with leadership skills to inspire and guide your teammates
- The ideal candidate will also have a proven track record of advancing engineering best practices within the organization
- 8+ years of experience in full-stack software development emphasizing modern web applications
- Expert-level proficiency in TypeScript, specifically in developing production-quality front-end applications
- Strong backend development skills in Python, particularly in AI/ML integration contexts
- 7+ years of experience in back-end services and API development in a distributed service-oriented architecture utilizing various paradigms (e.g., REST, RPC, GraphQL)
- Proven experience in developing AI-driven user interfaces, inclusive of conversational interfaces and intelligent data workflows
- Expertise in data modeling using various database and storage systems relevant to AI applications
- 5+ years experience designing and deploying resilient cloud services, using Docker and Kubernetes (e.g., AWS, GCP, Azure)
- Practical understanding of multiple architectural paradigms and design patterns specific to AI applications
- Boldness in vision and bravery in execution
- Direct and empathetic communication
- Dependability in fulfilling commitments
- Adaptability in the face of change
- A strong bias towards action
Benefits
- Benefits
- Paid Time Off (PTO)
- Health, Dental, Vision, and Life Insurance
- 401k Retirement Savings Plan
- Employee Discounts
- Voluntary benefits
Responsibilities
- In this role, you will be instrumental in advancing our AI technology platform and developing intelligent software products that drive significant impact
- You will have the chance to propose innovative solutions to real-world challenges, collaborate cross-functionally with both engineering teams and business units, and spearhead enhancements to user experiences through intelligent interfaces and workflows
- Design and develop scalable, reliable, and maintainable full-stack AI-enabled software solutions
- Create dynamic chat interfaces that effectively utilize AI capabilities, delivering outstanding user experiences
- Implement advanced form fills with provenance awareness and intelligent summarization to boost productivity and accuracy
- Establish flexible, reusable frameworks for AI-enabled applications that can be utilized throughout the organization
- Lead the architecture and system design for complex, distributed AI applications, aligning with strategic business and technical objectives
- Work collaboratively with product managers, designers, and business teams to translate strategic AI plans into actionable technical solutions
- Mentor engineers, promoting a culture of technical excellence, continuous learning, and knowledge sharing concerning AI application development
- Champion and instill best practices in engineering and drive initiatives to enhance system performance, code quality, and developer productivity
- Act as the technical lead for a small team of full stack engineers, providing guidance, mentorship, and direct support
Full Description
Senior AI Applications Engineer
Join our thriving organization as we strive to enhance our AI-powered products and services.
We are seeking talented software engineers who can go beyond mere coding to design impactful AI application solutions.
You will need a strong foundation in understanding business objectives and communicating effectively, along with leadership skills to inspire and guide your teammates.
In this role, you will be instrumental in advancing our AI technology platform and developing intelligent software products that drive significant impact.
Lead major technical initiatives across various platforms that support our ambitious AI strategy.
You will have the chance to propose innovative solutions to real-world challenges, collaborate cross-functionally with both engineering teams and business units, and spearhead enhancements to user experiences through intelligent interfaces and workflows.
The ideal candidate will also have a proven track record of advancing engineering best practices within the organization.
Key Responsibilities
• Design and develop scalable, reliable, and maintainable full-stack AI-enabled software solutions.
• Create dynamic chat interfaces that effectively utilize AI capabilities, delivering outstanding user experiences.
• Implement advanced form fills with provenance awareness and intelligent summarization to boost productivity and accuracy.
• Establish flexible, reusable frameworks for AI-enabled applications that can be utilized throughout the organization.
• Lead the architecture and system design for complex, distributed AI applications, aligning with strategic business and technical objectives.
• Work collaboratively with product managers, designers, and business teams to translate strategic AI plans into actionable technical solutions.
• Mentor engineers, promoting a culture of technical excellence, continuous learning, and knowledge sharing concerning AI application development.
• Champion and instill best practices in engineering and drive initiatives to enhance system performance, code quality, and developer productivity.
• Act as the technical lead for a small team of full stack engineers, providing guidance, mentorship, and direct support.
Qualifications
• 8+ years of experience in full-stack software development emphasizing modern web applications.
• Expert-level proficiency in TypeScript, specifically in developing production-quality front-end applications.
• Strong backend development skills in Python, particularly in AI/ML integration contexts.
• 7+ years of experience creating large-scale front-end applications using React (preferred) or other modern frameworks like Vue or Angular.
• 7+ years of experience in back-end services and API development in a distributed service-oriented architecture utilizing various paradigms (e.g., REST, RPC, GraphQL).
• Proven experience in developing AI-driven user interfaces, inclusive of conversational interfaces and intelligent data workflows.
• Expertise in data modeling using various database and storage systems relevant to AI applications.
• 5+ years experience designing and deploying resilient cloud services, using Docker and Kubernetes (e.g., AWS, GCP, Azure).
• Practical understanding of multiple architectural paradigms and design patterns specific to AI applications.
Preferred Qualifications
• Experience with AI SDK, assistant-ui, or similar AI-oriented TypeScript frameworks.
• Background in developing document viewing and manipulation interfaces, especially with PDFs.
• Prior experience in healthcare or health tech, particularly in regulated industries with data privacy and compliance challenges.
• Familiarity with LLM integration, prompt engineering, and Retrieval-Augmented Generation (RAG) architectures.
• Contributions to open-source AI application projects or frameworks.
Our Mission
At GeneDx, we leverage cutting-edge science to innovate in genetic disease detection and diagnosis, with over 20 years of established expertise in identifying rare disorders.
Our commitment is not only rooted in scientific rigor but is also focused on patient care improvement.
Our Culture
We prioritize an environment that nurtures creativity and innovation, emphasizing collaboration and community.
We value diverse perspectives and encourage every team member to contribute meaningfully.
Our collective goal is to drive impactful change in patient care.
Our cultural principles include:
• Boldness in vision and bravery in execution.
• Direct and empathetic communication.
• Dependability in fulfilling commitments.
• Adaptability in the face of change.
• A strong bias towards action.
Benefits
• Paid Time Off (PTO)
• Health, Dental, Vision, and Life Insurance
• 401k Retirement Savings Plan
• Employee Discounts
• Voluntary benefits
GeneDx is an Equal Opportunity Employer. All privacy policy information can be found here.

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